
| Species: | Rabbit |
| Applications: | WB IHC IF |
| Immunogen Range: | A recombinant protein of human NFYB |
| Clonality: | Polyclonal Antibody |
| Isotype: | IgG |
| GENE ID: | 4801 |
| Swiss Prot: | P25208 |
| Synonyms: | HAP3, CBF-A, CBF-B, NF-YB |
| Purification: | Affinity purification |
| Storage: | Store at -20oC (regular) or -80oC (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Background: | The protein encoded by this gene is one subunit of a trimeric complex, forming a highly conserved transcription factor that binds with high specificity to CCAAT motifs in the promoter regions in a variety of genes. This gene product, subunit B, forms a tight dimer with the C subunit, a prerequisite for subunit A association. The resulting trimer binds to DNA with high specificity and affinity. Subunits B and C each contain a histone-like motif. Observation of the histone nature of these subunits is supported by two types of evidence; protein sequence alignments and experiments with mutants. |
| Caculated MW: | 23kDa |
| Observed MW: | Refer to Figures |
| Applications: |
WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:20 - 1:100 |
| Reacitivity: | Human, Mouse, Rat |