ARP5978-01 [Polyclonal Antibody]
REST Rabbit Polyclonal Antibody
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Species:   Rabbit
Applications:   WB IF
Immunogen Range:   A recombinant protein of human REST
Clonality:   Polyclonal Antibody
Isotype:   IgG
GENE ID:   5978
Swiss Prot:   Q13127
Synonyms:   XBR, NRSF
Purification:   Affinity purification
Storage:   Store at -20oC (regular) or -80oC (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Background:   This gene encodes a transcriptional repressor that represses neuronal genes in non-neuronal tissues. It is a member of the Kruppel-type zinc finger transcription factor family. It represses transcription by binding a DNA sequence element called the neuron-restrictive silencer element. The protein is also found in undifferentiated neuronal progenitor cells and it is thought that this repressor may act as a master negative regular of neurogenesis. Alternatively spliced transcript variants have been described
Caculated MW:   122kDa
Observed MW:   Refer to Figures
Applications:   WB 1:500 - 1:2000
IF 1:50 - 1:200
Reacitivity:   Human
For research use only. Not intended for diagnostic or therapeutic use!
Additional information