ARP440275-01 [Polyclonal Antibody]
EIF2AK4 Rabbit Polyclonal Antibody
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Species:   Rabbit
Applications:   WB IHC IF
Immunogen Range:   A recombinant protein of human EIF2AK4
Clonality:   Polyclonal Antibody
Isotype:   IgG
GENE ID:   440275
Swiss Prot:   Q9P2K8
Synonyms:   GCN2, PVOD2
Purification:   Affinity purification
Storage:   Store at -20oC (regular) or -80oC (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Background:   This gene encodes a member of a family of kinases that phosphorylate the alpha subunit of eukaryotic translation initiation factor-2 (EIF2), resulting in the downregulaton of protein synthesis. The encoded protein responds to amino acid deprivation by binding uncharged transfer RNAs. It may also be activated by glucose deprivation and viral infection. Mutations in this gene have been found in individuals suffering from autosomal recessive pulmonary venoocclusive-disease-2.
Caculated MW:   187kDa
Observed MW:   Refer to Figures
Applications:   WB 1:500 - 1:2000
IHC 1:50 - 1:200
IF 1:20 - 1:100
Reacitivity:   Human, Rat
For research use only. Not intended for diagnostic or therapeutic use!
Additional information