Species: | Rabbit |
Applications: | WB IHC IF |
Immunogen Range: | A recombinant protein of human EIF2AK4 |
Clonality: | Polyclonal Antibody |
Isotype: | IgG |
GENE ID: | 440275 |
Swiss Prot: | Q9P2K8 |
Synonyms: | GCN2, PVOD2 |
Purification: | Affinity purification |
Storage: | Store at -20oC (regular) or -80oC (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Background: | This gene encodes a member of a family of kinases that phosphorylate the alpha subunit of eukaryotic translation initiation factor-2 (EIF2), resulting in the downregulaton of protein synthesis. The encoded protein responds to amino acid deprivation by binding uncharged transfer RNAs. It may also be activated by glucose deprivation and viral infection. Mutations in this gene have been found in individuals suffering from autosomal recessive pulmonary venoocclusive-disease-2. |
Caculated MW: | 187kDa |
Observed MW: | Refer to Figures |
Applications: |
WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:20 - 1:100 |
Reacitivity: | Human, Rat |