Species: | Rabbit |
Applications: | WB IHC IF |
Immunogen Range: | A recombinant protein of human NCR3 |
Clonality: | Polyclonal Antibody |
Isotype: | IgG |
GENE ID: | 259197 |
Swiss Prot: | O14931 |
Synonyms: | 1C7, MALS, CD337, LY117, NKp30 |
Purification: | Affinity purification |
Storage: | Store at -20oC (regular) or -80oC (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Background: | The protein encoded by this gene is a natural cytotoxicity receptor (NCR) that may aid NK cells in the lysis of tumor cells. The encoded protein interacts with CD3-zeta (CD247), a T-cell receptor. A single nucleotide polymorphism in the 5' untranslated region of this gene has been associated with mild malaria suceptibility. Three transcript variants encoding different isoforms have been found for this gene. |
Caculated MW: | 21kDa |
Observed MW: | Refer to Figures |
Applications: |
WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50- 1:100 |
Reacitivity: | Human |