
| Species: | Rabbit |
| Applications: | WB IHC IF |
| Immunogen Range: | A recombinant protein of human NDE1 |
| Clonality: | Polyclonal Antibody |
| Isotype: | IgG |
| GENE ID: | 54820 |
| Swiss Prot: | Q9NXR1 |
| Synonyms: | NDE, LIS4, MHAC, NUDE, NUDE1, HOM-TES-87 |
| Purification: | Affinity purification |
| Storage: | Store at -20oC (regular) or -80oC (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Background: | This gene encodes a member of the nuclear distribution E (NudE) family of proteins. The encoded protein is localized at the centrosome and interacts with other centrosome components as part of a multiprotein complex that regulates dynein function. This protein plays an essential role in microtubule organization, mitosis and neuronal migration. Mutations in this gene cause lissencephaly 4, a disorder characterized by lissencephaly, severe brain atrophy, microcephaly, and severe mental retardation. Alternative splicing results in multiple transcript variants. |
| Caculated MW: | 39kDa |
| Observed MW: | Refer to Figures |
| Applications: |
WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:20 - 1:100 |
| Reacitivity: | Human, Mouse |