Species: | Rabbit |
Applications: | WB IHC IF |
Immunogen Range: | A recombinant protein of human STAM2 |
Clonality: | Polyclonal Antibody |
Isotype: | IgG |
GENE ID: | 10254 |
Swiss Prot: | O75886 |
Synonyms: | Hbp, STAM2A, STAM2B |
Purification: | Affinity purification |
Storage: | Store at -20oC (regular) or -80oC (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Background: | The protein encoded by this gene is closely related to STAM, an adaptor protein involved in the downstream signaling of cytokine receptors, both of which contain a SH3 domain and the immunoreceptor tyrosine-based activation motif (ITAM). Similar to STAM, this protein acts downstream of JAK kinases, and is phosphorylated in response to cytokine stimulation. This protein and STAM thus are thought to exhibit compensatory effects on the signaling pathway downstream of JAK kinases upon cytokine stimulation. |
Caculated MW: | 58kDa |
Observed MW: | Refer to Figures |
Applications: |
WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:20 - 1:100 |
Reacitivity: | Human, Mouse, Rat |