Species: | Rabbit |
Applications: | WB IHC IF |
Immunogen Range: | A recombinant protein of human STK3 |
Clonality: | Polyclonal Antibody |
Isotype: | IgG |
GENE ID: | 6788 |
Swiss Prot: | Q13188 |
Synonyms: | KRS1, MST2 |
Purification: | Affinity purification |
Storage: | Store at -20oC (regular) or -80oC (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Background: | This gene encodes a serine/threonine protein kinase activated by proapoptotic molecules indicating the encoded protein functions as a growth suppressor. Cleavage of the protein product by caspase removes the inhibitory C-terminal portion. The N-terminal portion is transported to the nucleus where it homodimerizes to form the active kinase which promotes the condensation of chromatin during apoptosis. Multiple transcript variants encoding different isoforms have been found for this gene. |
Caculated MW: | 56kDa |
Observed MW: | Refer to Figures |
Applications: |
WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:20 - 1:100 |
Reacitivity: | Human, Rat |