ARP2287-01 [Polyclonal Antibody]
FKBP3 Rabbit Polyclonal Antibody
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Species:   Rabbit
Applications:   WB IHC IF
Immunogen Range:   A recombinant protein of human FKBP3
Clonality:   Polyclonal Antibody
Isotype:   IgG
GENE ID:   2287
Swiss Prot:   Q00688
Synonyms:   FKBP-3, FKBP25, PPIase, FKBP-25
Purification:   Affinity purification
Storage:   Store at -20oC (regular) or -80oC (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Background:   The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin, as well as histone deacetylases, the transcription factor YY1, casein kinase II, and nucleolin. It has a higher affinity for rapamycin than for FK506 and thus may be an important target molecule for immunosuppression by rapamycin.
Caculated MW:   25kDa
Observed MW:   Refer to Figures
Applications:   WB 1:500 - 1:2000
IHC 1:50 - 1:200
IF 1:20 - 1:100
Reacitivity:   Human
For research use only. Not intended for diagnostic or therapeutic use!
Additional information