Species: | Rabbit |
Applications: | WB IHC IF |
Immunogen Range: | A recombinant protein of human FKBP3 |
Clonality: | Polyclonal Antibody |
Isotype: | IgG |
GENE ID: | 2287 |
Swiss Prot: | Q00688 |
Synonyms: | FKBP-3, FKBP25, PPIase, FKBP-25 |
Purification: | Affinity purification |
Storage: | Store at -20oC (regular) or -80oC (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Background: | The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin, as well as histone deacetylases, the transcription factor YY1, casein kinase II, and nucleolin. It has a higher affinity for rapamycin than for FK506 and thus may be an important target molecule for immunosuppression by rapamycin. |
Caculated MW: | 25kDa |
Observed MW: | Refer to Figures |
Applications: |
WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:20 - 1:100 |
Reacitivity: | Human |