ARP1407-01
[Polyclonal Antibody]
CRY1 Rabbit Polyclonal Antibody
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Species: |
Rabbit |
Applications: |
WB IHC |
Immunogen Range: |
A recombinant protein of human CRY1 |
Clonality: |
Polyclonal Antibody |
Isotype: |
IgG |
GENE ID: |
1407 |
Swiss Prot: |
Q16526 |
Synonyms: |
PHLL1 |
Purification: |
Affinity purification |
Storage: |
Store at -20oC (regular) or -80oC (long term). Avoid freeze / thaw cycles.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Background: |
This gene encodes a flavin adenine dinucleotide-binding protein that is a key component of the circadian core oscillator complex, which regulates the circadian clock. This gene is upregulated by CLOCK/ARNTL heterodimers but then represses this upregulation in a feedback loop using PER/CRY heterodimers to interact with CLOCK/ARNTL. Polymorphisms in this gene have been associated with altered sleep patterns. The encoded protein is widely conserved across plants and animals. Loss of the related gene in mouse results in a shortened circadian cycle in complete darkness. |
Caculated MW: |
66kDa |
Observed MW: |
Refer to Figures |
Applications: |
WB 1:500 - 1:2000 IHC 1:50 - 1:200
|
Reacitivity: |
Human |
For research use only. Not intended for diagnostic or therapeutic use!