ARP6834-01
[Polyclonal Antibody]
SURF1 Rabbit Polyclonal Antibody
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Species: |
Rabbit |
Applications: |
WB IHC |
Immunogen Range: |
A recombinant protein of human SURF1 |
Clonality: |
Polyclonal Antibody |
Isotype: |
IgG |
GENE ID: |
6834 |
Swiss Prot: |
Q15526 |
Synonyms: |
|
Purification: |
Affinity purification |
Storage: |
Store at -20oC (regular) or -80oC (long term). Avoid freeze / thaw cycles.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Background: |
This gene encodes a protein localized to the inner mitochondrial membrane and thought to be involved in the biogenesis of the cytochrome c oxidase complex. The protein is a member of the SURF1 family, which includes the related yeast protein SHY1 and rickettsial protein RP733. The gene is located in the surfeit gene cluster, a group of very tightly linked genes that do not share sequence similarity, where it shares a bidirectional promoter with SURF2 on the opposite strand. Defects in this gene are a cause of Leigh syndrome, a severe neurological disorder that is commonly associated with systemic cytochrome c oxidase deficiency. |
Caculated MW: |
33kDa |
Observed MW: |
Refer to Figures |
Applications: |
WB 1:500 - 1:2000 IHC 1:50 - 1:200
|
Reacitivity: |
Human |
For research use only. Not intended for diagnostic or therapeutic use!