Species: | Rabbit |
Applications: | WB IHC IF |
Immunogen Range: | A recombinant protein of human SUFU |
Clonality: | Polyclonal Antibody |
Isotype: | IgG |
GENE ID: | 51684 |
Swiss Prot: | Q9UMX1 |
Synonyms: | SUFUH, SUFUXL, PRO1280 |
Purification: | Affinity purification |
Storage: | Store at -20oC (regular) or -80oC (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Background: | The Hedgehog signaling pathway plays an important role in early human development. The pathway is a signaling cascade that plays a role in pattern formation and cellular proliferation during development. This gene encodes a negative regulator of the hedgehog signaling pathway. Defects in this gene are a cause of medulloblastoma. Alternative splicing results in multiple transcript variants. |
Caculated MW: | 53kDa |
Observed MW: | Refer to Figures |
Applications: |
WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200 |
Reacitivity: | Human, Mouse, Rat |