ARP5511-01
[Polyclonal Antibody]
PPP1R8 Rabbit Polyclonal Antibody
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DATASHEET
| Species: |
Rabbit |
| Applications: |
WB IHC |
| Immunogen Range: |
A recombinant protein of human PPP1R8 |
| Clonality: |
Polyclonal Antibody |
| Isotype: |
IgG |
| GENE ID: |
5511 |
| Swiss Prot: |
Q12972 |
| Synonyms: |
ARD1, ARD-1, NIPP1, NIPP-1, PRO2047 |
| Purification: |
Affinity purification |
| Storage: |
Store at -20oC (regular) or -80oC (long term). Avoid freeze / thaw cycles.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Background: |
This gene, through alternative splicing, encodes three different isoforms. Two of the protein isoforms encoded by this gene are specific inhibitors of type 1 serine/threonine protein phosphatases and can bind but not cleave RNA. The third protein isoform lacks the phosphatase inhibitory function but is a single-strand endoribonuclease comparable to RNase E of E. coli. This isoform requires magnesium for its function and cleaves specific sites in A+U-rich regions of RNA. |
| Caculated MW: |
38kDa |
| Observed MW: |
Refer to Figures |
| Applications: |
WB 1:500 - 1:2000 IHC 1:50 - 1:200
|
| Reacitivity: |
Human, Mouse, Rat |
For research use only. Not intended for diagnostic or therapeutic use!