Species: | Mouse |
Applications: | WB IHC IF |
Immunogen Range: | KLH conjugated synthetic peptide derived from human PP-1B |
Clonality: | Polyclonal Antibody |
Isotype: | IgG |
GENE ID: | 5500 |
Swiss Prot: | P62140 |
Synonyms: | PP1B, PP-1B, PPP1CD, PP1beta, HEL-S-8p, Serine/threonine-protein phosphatase PP1-beta catalytic subunit, PPP1CB |
Purification: | Purified by Protein A. |
Storage: | Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months |
Background: | Protein phosphatase that associates with over 2 regulatory proteins to form highly specific holoenzymes which dephosphorylate hundreds of biological targets. Protein phosphatase (PP1) is essential for cell division, it participates in the regulation of glycogen metabolism, muscle contractility and protein synthesis. Involved in regulation of ionic conductances and long-term synaptic plasticity. Component of the PTW/PP1 phosphatase complex, which plays a role in the control of chromatin structure and cell cycle progression during the transition from mitosis into interphase. In balance with CSNK1D and CSNK1E, determines the circadian period length, through the regulation of the speed and rhythmicity of PER1 and PER2 phosphorylation. May dephosphorylate CSNK1D and CSNK1E. |
Caculated MW: | / |
Observed MW: | Refer to Figures |
Applications: |
WB 1:100-1:1000 IHC 1:100-1:500 IF 1:50-1:200 |
Reacitivity: | Human, Rat, Rabbit |