Species: | Rabbit |
Applications: | WB IHC IF |
Immunogen Range: | A recombinant protein of human NHLRC1 |
Clonality: | Polyclonal Antibody |
Isotype: | IgG |
GENE ID: | 378884 |
Swiss Prot: | Q6VVB1 |
Synonyms: | EPM2A, EPM2B, MALIN, bA204B7.2 |
Purification: | Affinity purification |
Storage: | Store at -20oC (regular) or -80oC (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Background: | The protein encoded by this gene is a single subunit E3 ubiquitin ligase. Laforin is polyubiquitinated by the encoded protein. Defects in this intronless gene lead to an accumulation of laforin and onset of Lafora disease, also known as progressive myoclonic epilepsy type 2 (EPM2). |
Caculated MW: | 42kDa |
Observed MW: | Refer to Figures |
Applications: |
WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200 |
Reacitivity: | Human |