Species: | Rabbit |
Applications: | WB IHC IF |
Immunogen Range: | A recombinant protein of human GAMT |
Clonality: | Polyclonal Antibody |
Isotype: | IgG |
GENE ID: | 2593 |
Swiss Prot: | Q14353 |
Synonyms: | PIG2, CCDS2, TP53I2, HEL-S-20 |
Purification: | Affinity purification |
Storage: | Store at -20oC (regular) or -80oC (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Background: | The protein encoded by this gene is a methyltransferase that converts guanidoacetate to creatine, using S-adenosylmethionine as the methyl donor. Defects in this gene have been implicated in neurologic syndromes and muscular hypotonia, probably due to creatine deficiency and accumulation of guanidinoacetate in the brain of affected individuals. Two transcript variants encoding different isoforms have been described for this gene. Pseudogenes of this gene are found on chromosomes 2 and 13. |
Caculated MW: | 26kDa |
Observed MW: | Refer to Figures |
Applications: |
WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200 |
Reacitivity: | Human |