Species: | Rabbit |
Applications: | WB IHC IF |
Immunogen Range: | A recombinant protein of human CRHBP |
Clonality: | Polyclonal Antibody |
Isotype: | IgG |
GENE ID: | 1393 |
Swiss Prot: | P24387 |
Synonyms: | CRFBP, CRF-BP |
Purification: | Affinity purification |
Storage: | Store at -20oC (regular) or -80oC (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Background: | Corticotropin-releasing hormone is a potent stimulator of synthesis and secretion of preopiomelanocortin-derived peptides. Although CRH concentrations in the human peripheral circulation are normally low, they increase throughout pregnancy and fall rapidly after parturition. Maternal plasma CRH probably originates from the placenta. Human plasma contains a CRH-binding protein which inactivates CRH and which may prevent inappropriate pituitary-adrenal stimulation in pregnancy. |
Caculated MW: | 36kDa |
Observed MW: | Refer to Figures |
Applications: |
WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50- 1:100 |
Reacitivity: | Human |