Species: | Rabbit |
Applications: | WB IHC IF |
Immunogen Range: | A recombinant protein of human LNX1 |
Clonality: | Polyclonal Antibody |
Isotype: | IgG |
GENE ID: | 84708 |
Swiss Prot: | Q8TBB1 |
Synonyms: | LNX, MPDZ, PDZRN2 |
Purification: | Affinity purification |
Storage: | Store at -20oC (regular) or -80oC (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Background: | This gene encodes a membrane-bound protein that is involved in signal transduction and protein interactions. The encoded product is an E3 ubiquitin-protein ligase, which mediates ubiquitination and subsequent proteasomal degradation of proteins containing phosphotyrosine binding (PTB) domains. This protein may play an important role in tumorogenesis. Alternatively spliced transcript variants encoding distinct isoforms have been described. A pseudogene, which is located on chromosome 17, has been identified for this gene. |
Caculated MW: | 80kDa |
Observed MW: | Refer to Figures |
Applications: |
WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50- 1:100 |
Reacitivity: | Human |