Species: | Rabbit |
Applications: | WB IHC IF |
Immunogen Range: | A recombinant protein of human PRAME |
Clonality: | Polyclonal Antibody |
Isotype: | IgG |
GENE ID: | 23532 |
Swiss Prot: | P78395 |
Synonyms: | MAPE, OIP4, CT130, OIP-4 |
Purification: | Affinity purification |
Storage: | Store at -20oC (regular) or -80oC (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Background: | This gene encodes an antigen that is preferentially expressed in human melanomas and that is recognized by cytolytic T lymphocytes. It is not expressed in normal tissues, except testis. The encoded protein acts as a repressor of retinoic acid receptor, and likely confers a growth advantage to cancer cells via this function. Alternative splicing results in multiple transcript variants. |
Caculated MW: | 57kDa |
Observed MW: | Refer to Figures |
Applications: |
WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50- 1:100 |
Reacitivity: | Human |