Species: | Rabbit |
Applications: | WB IHC IF |
Immunogen Range: | A recombinant protein of human PPOX |
Clonality: | Polyclonal Antibody |
Isotype: | IgG |
GENE ID: | 5498 |
Swiss Prot: | P50336 |
Synonyms: | VP, PPO, V290M |
Purification: | Affinity purification |
Storage: | Store at -20oC (regular) or -80oC (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Background: | This gene encodes the penultimate enzyme of heme biosynthesis, which catalyzes the 6-electron oxidation of protoporphyrinogen IX to form protoporphyrin IX. Mutations in this gene cause variegate porphyria, an autosomal dominant disorder of heme metabolism resulting from a deficiency in protoporphyrinogen oxidase, an enzyme located on the inner mitochondrial membrane. Alternatively spliced transcript variants encoding the same protein have been identified. |
Caculated MW: | 50kDa |
Observed MW: | Refer to Figures |
Applications: |
WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50- 1:100 |
Reacitivity: | Human, Mouse, Rat |