ARP3560-11
[Polyclonal Antibody]
IL2RB Rabbit Polyclonal Antibody
www.yhsbio.com
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DATASHEET
Species: |
Rabbit |
Applications: |
WB |
Immunogen Range: |
IL2RB (NP_000869.1, 1 a.a. ~ 551 a.a) full-length human protein |
Clonality: |
Polyclonal Antibody |
Isotype: |
/ |
GENE ID: |
3560 |
Swiss Prot: |
P14784 |
Synonyms: |
CD122, P70-75 |
Purification: |
Affinity purification |
Storage: |
Store at -20°C or lower in PBS(pH 7.4). Avoid freeze/thaw cycles. |
Background: |
The interleukin 2 receptor, which is involved in T cell-mediated immune responses, is present in 3 forms with respect to ability to bind interleukin 2. The low affinity form is a monomer of the alpha subunit and is not involved in signal transduction. The intermediate affinity form consists of an alpha/beta subunit heterodimer, while the high affinity form consists of an alpha/beta/gamma subunit heterotrimer. Both the intermediate and high affinity forms of the receptor are involved in receptor-mediated endocytosis and transduction of mitogenic signals from interleukin 2. The protein encoded by this gene represents the beta subunit and is a type I membrane protein. |
Caculated MW: |
60-70 kDa |
Observed MW: |
Refer to Figures |
Applications: |
|
Reacitivity: |
Human |
For research use only. Not intended for diagnostic or therapeutic use!