ARP3560-11 [Polyclonal Antibody]
IL2RB Rabbit Polyclonal Antibody
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Species:   Rabbit
Applications:   WB
Immunogen Range:   IL2RB (NP_000869.1, 1 a.a. ~ 551 a.a) full-length human protein
Clonality:   Polyclonal Antibody
Isotype:   /
GENE ID:   3560
Swiss Prot:   P14784
Synonyms:   CD122, P70-75
Purification:   Affinity purification
Storage:   Store at -20°C or lower in PBS(pH 7.4). Avoid freeze/thaw cycles.
Background:   The interleukin 2 receptor, which is involved in T cell-mediated immune responses, is present in 3 forms with respect to ability to bind interleukin 2. The low affinity form is a monomer of the alpha subunit and is not involved in signal transduction. The intermediate affinity form consists of an alpha/beta subunit heterodimer, while the high affinity form consists of an alpha/beta/gamma subunit heterotrimer. Both the intermediate and high affinity forms of the receptor are involved in receptor-mediated endocytosis and transduction of mitogenic signals from interleukin 2. The protein encoded by this gene represents the beta subunit and is a type I membrane protein.
Caculated MW:   60-70 kDa
Observed MW:   Refer to Figures
Applications:  
Reacitivity:   Human
For research use only. Not intended for diagnostic or therapeutic use!
Additional information