
| Species: | Rabbit |
| Applications: | WB IHC IP IF |
| Immunogen Range: | A recombinant protein of human FUS |
| Clonality: | Polyclonal Antibody |
| Isotype: | IgG |
| GENE ID: | 2521 |
| Swiss Prot: | P35637 |
| Synonyms: | TLS, ALS6, ETM4, FUS1, POMP75, HNRNPP2 |
| Purification: | Affinity purification |
| Storage: | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Background: | This gene encodes a multifunctional protein component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complex. The hnRNP complex is involved in pre-mRNA splicing and the export of fully processed mRNA to the cytoplasm. This protein belongs to the FET family of RNA-binding proteins which have been implicated in cellular processes that include regulation of gene expression, maintenance of genomic integrity and mRNA/microRNA processing. Alternative splicing results in multiple transcript variants. Defects in this gene result in amyotrophic lateral sclerosis type 6. |
| Caculated MW: | 75 kDa |
| Observed MW: | Refer to Figures |
| Applications: |
WB 1:500-1:2000 IHC 1:50-1:200 IF 1:50-1:100 |
| Reacitivity: | Human, Mouse, Rat |