Species: | Rabbit |
Applications: | WB IHC IP IF |
Immunogen Range: | A recombinant protein of human FUS |
Clonality: | Polyclonal Antibody |
Isotype: | IgG |
GENE ID: | 2521 |
Swiss Prot: | P35637 |
Synonyms: | TLS, ALS6, ETM4, FUS1, POMP75, HNRNPP2 |
Purification: | Affinity purification |
Storage: | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Background: | This gene encodes a multifunctional protein component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complex. The hnRNP complex is involved in pre-mRNA splicing and the export of fully processed mRNA to the cytoplasm. This protein belongs to the FET family of RNA-binding proteins which have been implicated in cellular processes that include regulation of gene expression, maintenance of genomic integrity and mRNA/microRNA processing. Alternative splicing results in multiple transcript variants. Defects in this gene result in amyotrophic lateral sclerosis type 6. |
Caculated MW: | 75 kDa |
Observed MW: | Refer to Figures |
Applications: |
WB 1:500-1:2000 IHC 1:50-1:200 IF 1:50-1:100 |
Reacitivity: | Human, Mouse, Rat |