ARP23421-01
[Polyclonal Antibody]
ITGB3BP Rabbit Polyclonal Antibody
www.yhsbio.com
market@yhsbio.com
support@yhsbio.com
+86-21-54651191
Room 703,Building 6,333# Guiping
Rd.,Xuhui District,Shanghai,China
DATASHEET
Species: |
Rabbit |
Applications: |
WB IHC |
Immunogen Range: |
A recombinant protein of human ITGB3BP |
Clonality: |
Polyclonal Antibody |
Isotype: |
IgG |
GENE ID: |
23421 |
Swiss Prot: |
Q13352 |
Synonyms: |
CENPR, NRIF3, TAP20, CENP-R, HSU37139 |
Purification: |
Affinity purification |
Storage: |
Store at -20oC or -80oC. Avoid freeze / thaw cycles.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Background: |
This gene encodes a transcriptional coregulator that binds to and enhances the activity of members of the nuclear receptor families, thyroid hormone receptors and retinoid X receptors. This protein also acts as a corepressor of NF-kappaB-dependent signaling. This protein induces apoptosis in breast cancer cells through a caspase 2-mediated signaling pathway. This protein is also a component of the centromere-specific histone H3 variant nucleosome associated complex (CENP-NAC) and may be involved in mitotic progression by recruiting the histone H3 variant CENP-A to the centromere. Alternate splicing results in multiple transcript variants. |
Caculated MW: |
20kDa |
Observed MW: |
Refer to Figures |
Applications: |
WB 1:500 - 1:2000 IHC 1:50 - 1:200
|
Reacitivity: |
Human |
For research use only. Not intended for diagnostic or therapeutic use!