ARP5588-11 [Polyclonal Antibody]
PRKCQ Rabbit Polyclonal Antibody
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Species:   Rabbit
Applications:   WB IHC ELISA
Immunogen Range:   A synthetic peptide (conjugated with KLH) corresponding to C-terminus of human PRKCQ
Clonality:   Polyclonal Antibody
Isotype:   /
GENE ID:   5588
Swiss Prot:   Q04759
Synonyms:   MGC12651, MGC141919, PRKCT, nPKC-theta
Purification:   Affinity purification
Storage:   Store at 4°C. For long term storage store at -20°C in PBS with 0.09% sodium azide. Avoid freeze/thaw cycles.
Background:   Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role. The protein encoded by this gene is one of the PKC family members. It is a calcium-independent and phospholipid-dependent protein kinase. This kinase is important for T-cell activation. It is required for the activation of the transcription factors NF-kappaB and AP-1, and may link the T cell receptor (TCR) signaling complex to the activation of the transcription factors.
Caculated MW:   81.90 kDa
Observed MW:   Refer to Figures
Applications:   WB 1:100-1:500
IHC 1:50-1:100
Reacitivity:   Human
For research use only. Not intended for diagnostic or therapeutic use!
Additional information