ARP11143-01
[Polyclonal Antibody]
KAT7 Rabbit Polyclonal Antibody
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Species: |
Rabbit |
Applications: |
WB IHC |
Immunogen Range: |
A recombinant protein of human KAT7 |
Clonality: |
Polyclonal Antibody |
Isotype: |
IgG |
GENE ID: |
11143 |
Swiss Prot: |
O95251 |
Synonyms: |
HBO1, HBOA, MYST2, ZC2HC7 |
Purification: |
Affinity purification |
Storage: |
Store at -20oC or -80oC. Avoid freeze / thaw cycles.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Background: |
MYST2, also named as HBO1, HBOa MOZ, YBF2/SAS3, SAS2 and TIP60 protein 2, belongs to the MYST (SAS/MOZ) family. It specifically represses AR mediated transcription. MYST2 is a candidate oncogene. It enhances the anchorage-independent growth of breast cancer cells.(PMID:19372580) MYST2 is a histone acetyltransferase (HAT) which could exert oncogenic function in breast cancer. It is an important downstream molecule of ERa, and ERK1/2 signaling pathway may involved in the expression of HBO1 increased by E2. |
Caculated MW: |
71kDa |
Observed MW: |
Refer to Figures |
Applications: |
WB 1:500 - 1:2000 IHC 1:50 - 1:200
|
Reacitivity: |
Human, Mouse, Rat, |
For research use only. Not intended for diagnostic or therapeutic use!