ARP8554-11
[Polyclonal Antibody]
PIAS1 Rabbit Polyclonal Antibody
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DATASHEET
| Species: |
Rabbit |
| Applications: |
WB IHC ELISA |
| Immunogen Range: |
A synthetic peptide (conjugated with KLH) corresponding to N-terminus of human PIAS1 |
| Clonality: |
Polyclonal Antibody |
| Isotype: |
/ |
| GENE ID: |
8554 |
| Swiss Prot: |
O75925 |
| Synonyms: |
DDXBP1, GBP, GU/RH-II, MGC141878, MGC141879, ZMIZ3 |
| Purification: |
Protein G purification |
| Storage: |
Store at 4°C. For long term storage store at -20°C in PBS with 0.09% sodium azide. Avoid freeze/thaw cycles. |
| Background: |
This gene encodes a member of the mammalian PIAS [protein inhibitor of activated STAT-1 (signal transducer and activator of transcription-1)] family. This member contains a putative zinc-binding motif and a highly acidic region. It inhibits STAT1-mediated gene activation and the DNA binding activity, binds to Gu protein/RNA helicase II/DEAD box polypeptide 21, and interacts with androgen receptor (AR). It functions in testis as a nuclear receptor transcriptional coregulator and may have a role in AR initiation and maintenance of spermatogenesis. |
| Caculated MW: |
76 kDa |
| Observed MW: |
Refer to Figures |
| Applications: |
WB 1:100-1:500 IHC 1:50-1:100
|
| Reacitivity: |
Human |
For research use only. Not intended for diagnostic or therapeutic use!