ARP8835-11 [Polyclonal Antibody]
SOCS2 Rabbit Polyclonal Antibody
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Species:   Rabbit
Applications:   WB
Immunogen Range:   A synthetic peptide corresponding to C-terminus of human SOCS2
Clonality:   Polyclonal Antibody
Isotype:   /
GENE ID:   8835
Swiss Prot:   O14508
Synonyms:   CIS2, Cish2, SOCS-2, SSI-2, SSI2, STATI2
Purification:   Affinity purification
Storage:   Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles.
Background:   This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by a subset of cytokines, including erythropoietin, GM-CSF, IL10 and interferon (IFN)-gamma. The protein encoded by this gene is found to interact with the cytoplasmic domain of insulin-like growth factor-1 receptor (IGF1R), and thus is thought to be involved in the regulation of IGF1R mediated cell signaling. Knockout studies in mice also suggested a regulatory role of this gene in IGF-1 related growth control.
Caculated MW:   22 kDa
Observed MW:   Refer to Figures
Applications:   WB 1 ug/Ml
Reacitivity:   Human, Rat
For research use only. Not intended for diagnostic or therapeutic use!
Additional information