Species: | Rabbit |
Applications: | WB IHC IF |
Immunogen Range: | A recombinant protein of human DCLRE1C |
Clonality: | Polyclonal Antibody |
Isotype: | IgG |
GENE ID: | 64421 |
Swiss Prot: | Q96SD1 |
Synonyms: | SCIDA, SNM1C, A-SCID, hSNM1C, RS-SCID, DCLREC1C |
Purification: | Affinity purification |
Storage: | Store at -20oC or -80oC. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Background: | This gene encodes a nuclear protein that is involved in V(D)J recombination and DNA repair. The protein has single-strand-specific 5'-3' exonuclease activity; it also exhibits endonuclease activity on 5' and 3' overhangs and hairpins when complexed with protein kinase, DNA-activated, catalytic polypeptide. Mutations in this gene cause Athabascan-type severe combined immunodeficiency (SCIDA). |
Caculated MW: | 78kDa |
Observed MW: | Refer to Figures |
Applications: |
WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50- 1:200 |
Reacitivity: | Human, Mouse, Rat |