ARP1024-11 [Polyclonal Antibody]
CDK8 Rabbit Polyclonal Antibody
www.yhsbio.com
market@yhsbio.com
support@yhsbio.com
+86-21-54651191
Room 703,Building 6,333# Guiping
Rd.,Xuhui District,Shanghai,China
DATASHEET
Species:   Rabbit
Applications:   WB ELISA
Immunogen Range:   A synthetic peptide (conjugated with KLH) corresponding to N-terminus of human CDK8
Clonality:   Polyclonal Antibody
Isotype:   IgG
GENE ID:   1024
Swiss Prot:   P49336
Synonyms:   K35, MGC12607, MGC126075
Purification:   Affinity purification
Storage:   Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles.
Background:   The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. This kinase and its regulatory subunit cyclin C are components of the RNA polymerase II holoenzyme complex, which phosphorylates the carboxy-terminal domain (CTD) of the largest subunit of RNA polymerase II. This kinase has also been shown to regulate transcription by targeting the CDK7/cyclin H subunits of the general transcription initiation factor IIH (TFIIH), thus providing a link between the 'Mediator-like' protein complexes and the basal transcription machinery.
Caculated MW:   53 kDa
Observed MW:   Refer to Figures
Applications:   WB 1:100-1:500
Reacitivity:   Human
For research use only. Not intended for diagnostic or therapeutic use!
Additional information