Species: | Rabbit |
Applications: | WB IHC IF |
Immunogen Range: | A recombinant protein of human PKP2 |
Clonality: | Polyclonal Antibody |
Isotype: | IgG |
GENE ID: | 5318 |
Swiss Prot: | Q99959 |
Synonyms: | ARVD9 |
Purification: | Affinity purification |
Storage: | Store at -20oC or -80oC. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Background: | This gene encodes a member of the arm-repeat (armadillo) and plakophilin gene families. Plakophilin proteins contain numerous armadillo repeats, localize to cell desmosomes and nuclei, and participate in linking cadherins to intermediate filaments in the cytoskeleton. This gene product may regulate the signaling activity of beta-catenin. Two alternately spliced transcripts encoding two protein isoforms have been identified. A processed pseudogene with high similarity to this locus has been mapped to chromosome 12p13. |
Caculated MW: | 94kDa |
Observed MW: | Refer to Figures |
Applications: |
WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50- 1:200 |
Reacitivity: | Human, Mouse, Rat, |