
| Species: | Rabbit |
| Applications: | WB IHC IF |
| Immunogen Range: | A recombinant protein of human HSD17B10 |
| Clonality: | Polyclonal Antibody |
| Isotype: | IgG |
| GENE ID: | 3028 |
| Swiss Prot: | Q99714 |
| Synonyms: | ABAD, CAMR, ERAB, HCD2, MHBD, HADH2, MRPP2, MRX17, MRX31, SCHAD, MRXS10, SDR5C1, 17b-HSD10, DUPXp11.22 |
| Purification: | Affinity purification |
| Storage: | Store at -20oC or -80oC. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Background: | This gene encodes 3-hydroxyacyl-CoA dehydrogenase type II, a member of the short-chain dehydrogenase/reductase superfamily. The gene product is a mitochondrial protein that catalyzes the oxidation of a wide variety of fatty acids, alcohols, and steroids. The protein has been implicated in the development of Alzheimer's disease, and mutations in the gene are the cause of 2-methyl-3-hydroxybutyryl-CoA dehydrogenase deficiency (MHBD). Several alternatively spliced transcript variants have been identified, but the full-length nature of only two transcript variants has been determined. |
| Caculated MW: | 27kDa |
| Observed MW: | Refer to Figures |
| Applications: |
WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50- 1:200 |
| Reacitivity: | Human, Mouse, Rat |