
| Species: | Rabbit |
| Applications: | WB IHC IF |
| Immunogen Range: | A recombinant protein of human CUL4B |
| Clonality: | Polyclonal Antibody |
| Isotype: | IgG |
| GENE ID: | 8450 |
| Swiss Prot: | O13620 |
| Synonyms: | hCUL4B |
| Purification: | Affinity purification |
| Storage: | Store at -20oC (regular) or -80oC (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Background: | This gene is a member of the cullin family. The encoded protein forms a complex that functions as an E3 ubiquitin ligase and catalyzes the polyubiquitination of specific protein substrates in the cell. The protein interacts with a ring finger protein, and is required for the proteolysis of several regulators of DNA replication including chromatin licensing and DNA replication factor 1 and cyclin E. Multiple transcript variants encoding different isoforms have been found for this gene. |
| Caculated MW: | 104kDa |
| Observed MW: | Refer to Figures |
| Applications: |
WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200 |
| Reacitivity: | Human, Mouse, Rat |