ARP5199-01 [Polyclonal Antibody]
CFP Rabbit Polyclonal Antibody
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Species:   Rabbit
Applications:   WB IHC IF
Immunogen Range:   A recombinant protein of human CFP
Clonality:   Polyclonal Antibody
Isotype:   IgG
GENE ID:   5199
Swiss Prot:   P27918
Synonyms:   BFD, PFC, PFD, PROPERDIN
Purification:   Affinity purification
Storage:   Store at -20oC or -80oC. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Background:   This gene encodes a plasma glycoprotein that positively regulates the alternative complement pathway of the innate immune system. This protein binds to many microbial surfaces and apoptotic cells and stabilizes the C3- and C5-convertase enzyme complexes in a feedback loop that ultimately leads to formation of the membrane attack complex and lysis of the target cell. Mutations in this gene result in two forms of properdin deficiency, which results in high susceptibility to meningococcal infections. Multiple alternatively spliced variants, encoding the same protein, have been identified.
Caculated MW:   51kDa
Observed MW:   Refer to Figures
Applications:   WB 1:500 - 1:2000
IHC 1:50 - 1:200
IF 1:50- 1:200
Reacitivity:   Human, Mouse, Rat,
For research use only. Not intended for diagnostic or therapeutic use!
Additional information