Species: | Rabbit |
Applications: | WB IHC IF |
Immunogen Range: | A recombinant protein of human RCAN1 |
Clonality: | Polyclonal Antibody |
Isotype: | IgG |
GENE ID: | 1827 |
Swiss Prot: | P53805 |
Synonyms: | CSP1, DSC1, RCN1, DSCR1, MCIP1, ADAPT78 |
Purification: | Affinity purification |
Storage: | Store at -20oC or -80oC. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Background: | The protein encoded by this gene interacts with calcineurin A and inhibits calcineurin-dependent signaling pathways, possibly affecting central nervous system development. This gene is located in the minimal candidate region for the Down syndrome phenotype, and is overexpressed in the brain of Down syndrome fetuses. Chronic overexpression of this gene may lead to neurofibrillary tangles such as those associated with Alzheimer disease. Alternative splicing results in multiple transcript variants. |
Caculated MW: | 28kDa |
Observed MW: | Refer to Figures |
Applications: |
WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50- 1:200 |
Reacitivity: | Human, Mouse, Rat, |