ARP1827-01 [Polyclonal Antibody]
RCAN1 Rabbit Polyclonal Antibody
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Species:   Rabbit
Applications:   WB IHC IF
Immunogen Range:   A recombinant protein of human RCAN1
Clonality:   Polyclonal Antibody
Isotype:   IgG
GENE ID:   1827
Swiss Prot:   P53805
Synonyms:   CSP1, DSC1, RCN1, DSCR1, MCIP1, ADAPT78
Purification:   Affinity purification
Storage:   Store at -20oC or -80oC. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Background:   The protein encoded by this gene interacts with calcineurin A and inhibits calcineurin-dependent signaling pathways, possibly affecting central nervous system development. This gene is located in the minimal candidate region for the Down syndrome phenotype, and is overexpressed in the brain of Down syndrome fetuses. Chronic overexpression of this gene may lead to neurofibrillary tangles such as those associated with Alzheimer disease. Alternative splicing results in multiple transcript variants.
Caculated MW:   28kDa
Observed MW:   Refer to Figures
Applications:   WB 1:500 - 1:2000
IHC 1:50 - 1:200
IF 1:50- 1:200
Reacitivity:   Human, Mouse, Rat,
For research use only. Not intended for diagnostic or therapeutic use!
Additional information