
| Species: | Rabbit |
| Applications: | WB IHC IF |
| Immunogen Range: | A recombinant protein of human GCLM |
| Clonality: | Polyclonal Antibody |
| Isotype: | IgG |
| GENE ID: | 2730 |
| Swiss Prot: | P48507 |
| Synonyms: | GCLM, GLCLR, Glutamate--cysteine ligase regulatory subunit, GCS light chain, Gamma-ECS regulatory subunit |
| Purification: | Affinity purification |
| Storage: | Store at -20oC or -80oC. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Background: | Glutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase, is the first rate limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. Gamma glutamylcysteine synthetase deficiency has been implicated in some forms of hemolytic anemia. |
| Caculated MW: | 30kDa |
| Observed MW: | Refer to Figures |
| Applications: |
WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50- 1:200 |
| Reacitivity: | Human, Mouse, Rat, |