Species: | Rabbit |
Applications: | WB IHC IF |
Immunogen Range: | A recombinant protein of human RACGAP1 |
Clonality: | Polyclonal Antibody |
Isotype: | IgG |
GENE ID: | 29127 |
Swiss Prot: | Q9H0H5 |
Synonyms: | CYK4, ID-GAP, HsCYK-4, MgcRacGAP |
Purification: | Affinity purification |
Storage: | Store at -20oC or -80oC. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Background: | The protein encoded by this gene belongs to the GTPase-activating protein (GAP) family. GAPs bind activated forms of Rho GTPases and stimulate GTP hydrolysis. Through this catalytic function, GAPs negatively regulate Rho-mediated signals. This protein plays a regulatory role in initiation of cytokinesis, controlling cell growth and differentiation of hematopoietic cells, regulating spermatogenesis, and in neuronal proliferation. Alternatively spliced transcript variants have been found for this gene. |
Caculated MW: | 71kDa |
Observed MW: | Refer to Figures |
Applications: |
WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50- 1:200 |
Reacitivity: | Human, Mouse, Rat |