ARP23533-01
[Polyclonal Antibody]
PIK3R5 Rabbit Polyclonal Antibody
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DATASHEET
Species: |
Rabbit |
Applications: |
WB IF |
Immunogen Range: |
A recombinant protein of human PIK3R5 |
Clonality: |
Polyclonal Antibody |
Isotype: |
IgG |
GENE ID: |
23533 |
Swiss Prot: |
Q8WYR1 |
Synonyms: |
p101, FOAP-2, P101-PI3K, F730038I15Rik |
Purification: |
Affinity purification |
Storage: |
Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Background: |
Phosphatidylinositol 3-kinases (PI3Ks) phosphorylate the inositol ring of phosphatidylinositol at the 3-prime position, and play important roles in cell growth, proliferation, differentiation, motility, survival and intracellular trafficking. The PI3Ks are divided into three classes: I, II and III, and only the class I PI3Ks are involved in oncogenesis. This gene encodes the 101 kD regulatory subunit of the class I PI3K gamma complex, which is a dimeric enzyme, consisting of a 110 kD catalytic subunit gamma and a regulatory subunit of either 55, 87 or 101 kD. This protein recruits the catalytic subunit from the cytosol to the plasma membrane through high-affinity interaction with G-beta-gamma proteins. Multiple alternatively spliced transcript variants encoding two distinct isoforms have been found. |
Caculated MW: |
97 kDa |
Observed MW: |
Refer to Figures |
Applications: |
WB 1:500-1:2000 IF 1:50-1:100
|
Reacitivity: |
Human, Mouse, Rat |
For research use only. Not intended for diagnostic or therapeutic use!