ARP7942-01 [Polyclonal Antibody]
TFEB Rabbit Polyclonal Antibody
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Species:   Rabbit
Applications:   WB IHC IP IF
Immunogen Range:   A recombinant protein of human TFEB
Clonality:   Polyclonal Antibody
Isotype:   IgG
GENE ID:   7942
Swiss Prot:   P19484
Synonyms:   AlphaTFEB, bHLHe35, TCFEB, TFEB, transcription factor EB
Purification:   Affinity purification
Storage:   Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles.
Background:   Transcription factor EB(TFEB) is one of the transcription factors that contain a basic HLH-ZIP domain(for DNA binding ) and HLH and ZIP domains( for loigomerization). TFEB specifically recognizes and binds to E-box sequences, which required dimerization with itself or another MiT/TFE family member. It plays a role in T-cell-dependent antibody responses to activated CD4+ T-cells and thymus-dependent humoral immunity once associated with TFE3. It also activates lysosomal gene by binding the CLEAR-box sequence in the regulatory region. It involves in the signal transduction processes required for normal vascularization of the placenta. This is a rabbit polyclonal antibody raised against the full length of human TFEB.
Caculated MW:   53 kDa
Observed MW:   Refer to Figures
Applications:   WB 1:500-1:1000
IHC 1:50-1:100
IF 1:50-1:100
Reacitivity:   Human, Mouse, Rat
For research use only. Not intended for diagnostic or therapeutic use!
Additional information