Species: | Rabbit |
Applications: | WB IHC IP IF |
Immunogen Range: | A recombinant protein of human TFEB |
Clonality: | Polyclonal Antibody |
Isotype: | IgG |
GENE ID: | 7942 |
Swiss Prot: | P19484 |
Synonyms: | AlphaTFEB, bHLHe35, TCFEB, TFEB, transcription factor EB |
Purification: | Affinity purification |
Storage: | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Background: | Transcription factor EB(TFEB) is one of the transcription factors that contain a basic HLH-ZIP domain(for DNA binding ) and HLH and ZIP domains( for loigomerization). TFEB specifically recognizes and binds to E-box sequences, which required dimerization with itself or another MiT/TFE family member. It plays a role in T-cell-dependent antibody responses to activated CD4+ T-cells and thymus-dependent humoral immunity once associated with TFE3. It also activates lysosomal gene by binding the CLEAR-box sequence in the regulatory region. It involves in the signal transduction processes required for normal vascularization of the placenta. This is a rabbit polyclonal antibody raised against the full length of human TFEB. |
Caculated MW: | 53 kDa |
Observed MW: | Refer to Figures |
Applications: |
WB 1:500-1:1000 IHC 1:50-1:100 IF 1:50-1:100 |
Reacitivity: | Human, Mouse, Rat |