ARP7296-01 [Polyclonal Antibody]
TXNRD1 Rabbit Polyclonal Antibody
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Species:   Rabbit
Applications:   WB IHC IP IF FC
Immunogen Range:   A recombinant protein of human TXNRD1
Clonality:   Polyclonal Antibody
Isotype:   IgG
GENE ID:   7296
Swiss Prot:   Q16881
Synonyms:   TR, TR1, TXNR, TRXR1, GRIM-12
Purification:   Affinity purification
Storage:   Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles.
Background:   This gene encodes a member of the family of pyridine nucleotide oxidoreductases. This protein reduces thioredoxins as well as other substrates, and plays a role in selenium metabolism and protection against oxidative stress. The functional enzyme is thought to be a homodimer which uses FAD as a cofactor. Each subunit contains a selenocysteine (Sec) residue which is required for catalytic activity. The selenocysteine is encoded by the UGA codon that normally signals translation termination. The 3' UTR of selenocysteine-containing genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Alternative splicing results in several transcript variants encoding the same or different isoforms.
Caculated MW:   55 kDa
Observed MW:   Refer to Figures
Applications:   WB 1:500-1:2000
IHC 1:50-1:200
IF 1:50-1:100
FC 1:20-1:50
Reacitivity:   Human, Mouse, Rat
For research use only. Not intended for diagnostic or therapeutic use!
Additional information