ARP2289-01
[Polyclonal Antibody]
FKBP5 Rabbit Polyclonal Antibody
www.yhsbio.com
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DATASHEET
Species: |
Rabbit |
Applications: |
WB IP IHC |
Immunogen Range: |
A recombinant protein of human FKBP5 |
Clonality: |
Polyclonal Antibody |
Isotype: |
IgG |
GENE ID: |
2289 |
Swiss Prot: |
Q13451 |
Synonyms: |
P54, AIG6, FKBP51, FKBP54, PPIase, Ptg-10 |
Purification: |
Affinity purification |
Storage: |
Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Background: |
The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds to the immunosuppressants FK506 and rapamycin. It is thought to mediate calcineurin inhibition. It also interacts functionally with mature hetero-oligomeric progesterone receptor complexes along with the 90 kDa heat shock protein and P23 protein. This gene has been found to have multiple polyadenylation sites. Alternative splicing results in multiple transcript variants. |
Caculated MW: |
51 kDa |
Observed MW: |
Refer to Figures |
Applications: |
WB 1:200-1:2000 IHC 1:50-1:200
|
Reacitivity: |
Human, Mouse, Rat |
For research use only. Not intended for diagnostic or therapeutic use!