ARP2903-01 [Polyclonal Antibody]
GRIN2A Rabbit Polyclonal Antibody
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Species:   Rabbit
Applications:   WB IF
Immunogen Range:   A synthetic peptide of human GRIN2A
Clonality:   Polyclonal Antibody
Isotype:   IgG
GENE ID:   2903
Swiss Prot:   Q12879
Synonyms:   LKS, EPND, FESD, NR2A, GluN2A, NMDAR2A
Purification:   Affinity purification
Storage:   Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles.
Background:   This gene encodes a member of the glutamate-gated ion channel protein family. The encoded protein is an N-methyl-D-aspartate (NMDA) receptor subunit. NMDA receptors are both ligand-gated and voltage-dependent, and are involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. These receptors are permeable to calcium ions, and activation results in a calcium influx into post-synaptic cells, which results in the activation of several signaling cascades. Disruption of this gene is associated with focal epilepsy and speech disorder with or without mental retardation. Alternative splicing results in multiple transcript variants.
Caculated MW:   165 kDa
Observed MW:   Refer to Figures
Applications:   WB 1:200-1:2000
IF 1:50-1:100
Reacitivity:   Human
For research use only. Not intended for diagnostic or therapeutic use!
Additional information