ARP3833-01 [Polyclonal Antibody]
KIFC1 Rabbit Polyclonal Antibody
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Species:   Rabbit
Applications:   WB IHC IF
Immunogen Range:   A recombinant protein of human KIFC1
Clonality:   Polyclonal Antibody
Isotype:   IgG
GENE ID:   3833
Swiss Prot:   Q9BW19
Synonyms:   HSET, KNSL2
Purification:   Affinity purification
Storage:   Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles.
Background:   Kinesin superfamily proteins (KIFs) are molecular motors that drive directional, microtubule-dependent intracellular transport of membrane-bound organelles and other macromolecules (e.g. proteins, nucleic acids). The intracellular transport functions of KIFs are fundamentally important for a variety of cellular functions, including mitotic and meiotic division, motility/migration, hormone and neurotransmitter release, and differentiation (1-4). Disruptions to KIF-mediated intracellular transport have been linked with a variety of pathologies, ranging from tumorigenesis to defects in higher order brain function such as learning and memory (4-6).KIFC1/HSET is a minus-end directed KIF involved in the processing and movement of early endocytic vesicles (7,8), as well as microtubule crosslinking and spindle assembly (9,10).
Caculated MW:   74 kDa
Observed MW:   Refer to Figures
Applications:   WB 1:200-1:2000
IHC 1:50-1:200
IF 1:50-1:100
Reacitivity:   Human, Mouse, Rat
For research use only. Not intended for diagnostic or therapeutic use!
Additional information