Species: | Rabbit |
Applications: | WB IHC IF |
Immunogen Range: | A recombinant protein of human MAP2K6 |
Clonality: | Polyclonal Antibody |
Isotype: | IgG |
GENE ID: | 5608 |
Swiss Prot: | P52564 |
Synonyms: | MAPKK6, MEK6, MKK6, PRKMK6, SAPKK3 |
Purification: | Affinity purification |
Storage: | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Background: | This gene encodes a member of the dual specificity protein kinase family, which functions as a mitogen-activatedprotein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as anintegration point for multiple biochemical signals. This protein phosphorylates and activates p38 MAP kinase inresponse to inflammatory cytokines or environmental stress. As an essential component of p38 MAP kinase mediatedsignal transduction pathway, this gene is involved in many cellular processes such as stress induced cell cycle arrest, transcription activation and apoptosis. |
Caculated MW: | 37 kDa |
Observed MW: | Refer to Figures |
Applications: |
WB 1:500-1:2000 IHC 1:50-1:200 IF 1:50-1:200 |
Reacitivity: | Human, Mouse, Rat |