Species: | Rabbit |
Applications: | WB IHC IF |
Immunogen Range: | A recombinant protein of human NEDD9 |
Clonality: | Polyclonal Antibody |
Isotype: | IgG |
GENE ID: | 4739 |
Swiss Prot: | Q14511 |
Synonyms: | CAS2, CASL, HEF1, CAS-L, CASS2 |
Purification: | Affinity purification |
Storage: | Store at -20oC (regular) or -80oC (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Background: | The protein encoded by this gene is a member of the CRK-associated substrates family. Members of this family are adhesion docking molecules that mediate protein-protein interactions for signal transduction pathways. This protein is a focal adhesion protein that acts as a scaffold to regulate signaling complexes important in cell attachment, migration and invasion as well as apoptosis and the cell cycle. This protein has also been reported to have a role in cancer metastasis. Alternative splicing results in multiple transcript variants. |
Caculated MW: | 92kDa |
Observed MW: | Refer to Figures |
Applications: |
WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200 |
Reacitivity: | Human, Mouse, Rat |