ARP29128-01
[Polyclonal Antibody]
UHRF1 Rabbit Polyclonal Antibody
www.yhsbio.com
market@yhsbio.com
support@yhsbio.com
+86-21-54651191
Room 703,Building 6,333# Guiping
Rd.,Xuhui District,Shanghai,China
market@yhsbio.com
support@yhsbio.com
+86-21-54651191
Room 703,Building 6,333# Guiping
Rd.,Xuhui District,Shanghai,China
DATASHEET
| Species: | Rabbit |
| Applications: | WB IHC IF IP CHIP |
| Immunogen Range: | A recombinant protein of human UHRF1 |
| Clonality: | Polyclonal Antibody |
| Isotype: | IgG |
| GENE ID: | 29128 |
| Swiss Prot: | Q96T88 |
| Synonyms: | FLJ21925, ICBP90, MGC138707, Np95, RNF106, hNP95 |
| Purification: | Affinity purification |
| Storage: | Store at -20oC or -80oC. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Background: | UHRF1, also named as ICBP90, NP95 and RNF106, is a putative E3 ubiquitin-protein ligase. It may participate in methylation-dependent transcriptional regulation. UHRF1 binds to inverted 5'-CCAAT-3' box 2 in the TOP2A promoter, and activates TOP2A expression. It is important for G1/S transition and may be involved in DNA repair and chromosomal stability. UHRF1's ability to repress its direct target gene expression is dependent on PHD(UHRF1) binding to unmodified H3R2. |
| Caculated MW: | 91kDa |
| Observed MW: | Refer to Figures |
| Applications: |
WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:20- 1:50 ChIP 1:20- 1:50 |
| Reacitivity: | Human, |
For research use only. Not intended for diagnostic or therapeutic use!
Additional information
