Species: | Rabbit |
Applications: | WB IHC IF |
Immunogen Range: | A recombinant protein of human MBD3 |
Clonality: | Polyclonal Antibody |
Isotype: | IgG |
GENE ID: | 53615 |
Swiss Prot: | O95983 |
Synonyms: | ABCLONAL网站没有 |
Purification: | Affinity purification |
Storage: | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Background: | DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development. This gene belongs to a family of nuclear proteins which are characterized by the presence of a methyl-CpG binding domain (MBD). The encoded protein is a subunit of the NuRD, a multisubunit complex containing nucleosome remodeling and histone deacetylase activities. Unlike the other family members, the encoded protein is not capable of binding to methylated DNA. The protein mediates the association of metastasis-associated protein 2 with the core histone deacetylase complex. Alternative splicing results in multiple transcript variants of this gene. |
Caculated MW: | 33 kDa |
Observed MW: | Refer to Figures |
Applications: |
WB 1:200-1:2000 IHC 1:50-1:200 IF 1:50-1:200 |
Reacitivity: | Human, Mouse, Rat |