ARP5378-01 [Polyclonal Antibody]
PMS1 Rabbit Polyclonal Antibody
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Species:   Rabbit
Applications:   WB IHC
Immunogen Range:   A recombinant protein of human PMS1
Clonality:   Polyclonal Antibody
Isotype:   IgG
GENE ID:   5378
Swiss Prot:   P54277
Synonyms:   DKFZp781M0253, FLJ98259, HNPCC3, PMSL1, hPMS1, PMS1
Purification:   Affinity purification
Storage:   Store at -20oC (regular) or -80oC (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Background:   PMS1 belongs to the DNA mismatch repair mutL/hexB family. It is thought to be involved in the repair of DNA mismatches, and it can form heterodimers with MLH1, a known DNA mismatch repair protein. Mutations in PMS1 cause hereditary nonpolyposis colorectal cancer type 3 (HNPCC3) either alone or in combination with mutations in other proteins involved in the HNPCC phenotype, which is also known as Lynch syndrome (1). 1. Entrez Gene: gene-centered information at NCBI. Nucleic Acids Res. 2005 Jan 1;33:D54-8.
Caculated MW:   106kDa
Observed MW:   Refer to Figures
Applications:   WB 1:500 - 1:2000
IHC 1:50 - 1:200
Reacitivity:   Human, Rat
For research use only. Not intended for diagnostic or therapeutic use!
Additional information