Species: | Rabbit |
Applications: | WB IHC IP IF |
Immunogen Range: | A recombinant protein of human PLCG2 |
Clonality: | Polyclonal Antibody |
Isotype: | IgG |
GENE ID: | 5336 |
Swiss Prot: | P16885 |
Synonyms: | FCAS3, APLAID, RP11-510J16.3 |
Purification: | Affinity purification |
Storage: | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Background: | The protein encoded by this gene is a transmembrane signaling enzyme that catalyzes the conversion of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate to 1D-myo-inositol 1,4,5-trisphosphate (IP3) and diacylglycerol (DAG), using calcium as a cofactor. IP3 and DAG are second messenger molecules important for transmitting signals from growth factor receptors and immune system receptors across the cell membrane. |
Caculated MW: | 150 kDa |
Observed MW: | Refer to Figures |
Applications: |
WB 1:500-1:2000 IHC 1:50-1:200 IF 1:20-1:100 |
Reacitivity: | Human, Mouse, Rat |