
| Species: | Rabbit |
| Applications: | WB IHC IF |
| Immunogen Range: | A recombinant protein of human IFI16 |
| Clonality: | Polyclonal Antibody |
| Isotype: | IgG |
| GENE ID: | 3428 |
| Swiss Prot: | Q16666 |
| Synonyms: | PYHIN2, IFNGIP1 |
| Purification: | Affinity purification |
| Storage: | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Background: | This gene encodes a member of the HIN-200 (hematopoietic interferon-inducible nuclear antigens with 200 amino acid repeats) family of cytokines. The encoded protein contains domains involved in DNA binding, transcriptional regulation, and protein-protein interactions. The protein localizes to the nucleoplasm and nucleoli, and interacts with p53 and retinoblastoma-1. It modulates p53 function, and inhibits cell growth in the Ras/Raf signaling pathway. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
| Caculated MW: | 88 kDa |
| Observed MW: | Refer to Figures |
| Applications: |
WB 1:500-1:2000 IHC 1:50-1:200 IF 1:50-1:200 |
| Reacitivity: | Human, Mouse |