Species: | Rabbit |
Applications: | WB IHC IF |
Immunogen Range: | A recombinant protein of human ELAVL1 |
Clonality: | Polyclonal Antibody |
Isotype: | IgG |
GENE ID: | 1994 |
Swiss Prot: | Q15717 |
Synonyms: | HUR, Hua, MelG, ELAV1 |
Purification: | Affinity purification |
Storage: | Store at -20oC or -80oC. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Background: | The protein encoded by this gene is a member of the ELAVL family of RNA-binding proteins that contain several RNA recognition motifs, and selectively bind AU-rich elements (AREs) found in the 3' untranslated regions of mRNAs. AREs signal degradation of mRNAs as a means to regulate gene expression, thus by binding AREs, the ELAVL family of proteins play a role in stabilizing ARE-containing mRNAs. This gene has been implicated in a variety of biological processes and has been linked to a number of diseases, including cancer. It is highly expressed in many cancers, and could be potentially useful in cancer diagnosis, prognosis, and therapy. [provided by RefSeq, Sep 2012] |
Caculated MW: | 36kDa |
Observed MW: | Refer to Figures |
Applications: |
WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50- 1:200 |
Reacitivity: | Human, Mouse, Rat |