ARP3456-01 [Polyclonal Antibody]
IFNB1 Rabbit Polyclonal Antibody
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Species:   Rabbit
Applications:   WB IHC IF
Immunogen Range:   A recombinant protein of human IFNB1
Clonality:   Polyclonal Antibody
Isotype:   IgG
GENE ID:   3456
Swiss Prot:   P01574
Synonyms:   IFNB1,IFB,IFF, IFNB,MGC96956
Purification:   Affinity purification
Storage:   Store at -20oC or -80oC. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Background:   The genes encoding type I interferons (IFNs), which include 14 IFN-? genes, one IFN-∫ gene, one IFN-w (also known as IFN-? II1) gene, and a number of IFN-w pseudogenes, are clustered on human chromosome 9. Interferons-? and -∫ are cytokines that are widely known to induce potent antiviral activity. IFN-? and -∫ exert a variety of other biological effects, including antitumor and immunomodulatory activities and are increasingly used clinically to treat a range of malignancies, myelodysplasias and autoimmune diseases. IFN-w is antigenically different from human IFN-?, IFN-∫ or IFN-?, but is a component of natural mixtures of IFN species produced by virus-induced leukocytes or Burkitt's lymphoma cells. The type I interferon receptor (IFN-?R) interacts with IFN-?, IFN-∫ and IFN-w, and seems to be a multisubunit receptor.
Caculated MW:   22kDa
Observed MW:   Refer to Figures
Applications:   WB 1:500 - 1:2000
IHC 1:50 - 1:200
IF 1:50- 1:200
Reacitivity:   Human,
For research use only. Not intended for diagnostic or therapeutic use!
Additional information